Airflow4 Clinical Trial Marketing & Screening Materials System

Project Overview

This clinical trial materials system case study demonstrates how coordinated flyer design, brochure design, and screening guide development were used to create a unified suite of marketing and clinical tools that support patient recruitment, education, and staff workflow.

Client: Nuvaria
Client Location: Minneapolis, MN
Industry: Clinical Research / Healthcare
Project Type: Clinical Trial Marketing & Screening Materials System
Deliverables: Recruitment Flyer, Trifold Brochure, Patient Screening Guide
Purpose: Support patient recruitment, education, and eligibility screening
Use Case: Physician office discussions, patient handouts, and clinical intake workflows
Distribution: Printed materials and digital files used across participating clinical sites

Client Background

Challenge

Design Approach

Deliverables

Services Provided

Results

Meet the Designer

Related Projects

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Clinical trial trifold brochure design for Airflow4 study showing cover layout
Clinical trial patient screening guide design showing icon-based overview and structured eligibility layout
Clinical trial patient recruitment flyer design for Airflow4 study showing structured layout and patient information
Clinical trial brochure panel with QR code linking to enrollment website

Project Summary

As the AIRFLOW clinical study progressed into a new phase, Nuvaira required a coordinated update across all patient-facing and staff-facing materials. Rather than redesigning each piece independently, the Airflow4 Clinical Trial Materials System was developed as a unified set of tools that work together to support recruitment, education, and screening.

The system includes a recruitment flyer for quick awareness, a trifold brochure for deeper patient education, and a patient screening guide designed for physician staff. Each piece serves a distinct role while maintaining consistency in structure, visual language, and usability across the full patient journey.

Client Background

Nuvaira is a medical device company focused on developing therapies for people with obstructive lung disease, particularly COPD. The company’s clinical research program includes the AIRFLOW studies, which evaluate a bronchoscopic treatment designed to improve outcomes for patients with chronic obstructive pulmonary disease. These studies rely on clear, structured materials to support both patient recruitment and clinical workflow efficiency across participating sites.

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Challenge

Aligning patient-facing and staff-facing materials into a cohesive, functional system

The project required more than updating individual assets. Each piece needed to serve a different audience and purpose while remaining consistent and easy to use across clinical environments.

Patient-facing materials needed to clearly communicate study information and support enrollment, while staff-facing tools needed to enable fast and accurate eligibility screening. At the same time, all materials had to remain compliant, readable, and adaptable as the study evolved.

Without a coordinated approach, this type of project often results in disconnected materials, inconsistent messaging, and increased friction for both patients and clinical staff.

Design Approach

The Airflow4 Clinical Trial Materials System was designed as a coordinated framework rather than a set of standalone pieces. Each asset was structured to support a specific role within the patient journey while maintaining consistency across layout, hierarchy, and visual language.

Because clinical trial materials often involve complex information and time-sensitive use, the system was designed to reduce cognitive load and improve comprehension. Print materials are proven to require less mental effort to process, with studies showing a 21% reduction in cognitive effort, making them more effective for communicating structured information in real-world clinical environments (Temple University | Neural Decision Making Study | 2026).

Material Roles Within the System

Clinical trial patient recruitment flyer design for Airflow4 study showing structured layout and patient information

The Airflow4 recruitment flyer design was created for quick visibility and initial patient engagement, providing a high-level overview that supports immediate understanding in clinical settings.

Full layout of trifold clinical trial brochure showing cover and interior panels

The trifold brochure design extends that interaction, offering a more detailed, take-home resource that allows patients to review study information at their own pace and access additional details through QR-based enrollment and education

Clinical trial patient screening guide design showing icon-based overview and structured eligibility layout

The patient screening guide shifts focus to internal workflow, giving physician staff a structured tool for evaluating eligibility through a combination of visual cues and detailed checklist criteria.

System-Level Design Decisions

Consistency across all materials was critical. Layout structures, spacing, typography, and content organization were aligned to create a unified experience, reducing confusion and improving usability across different touchpoints.

All files were built using paragraph and character styles, creating a scalable system that supports efficient updates and maintains consistency as study materials evolve. This approach ensures that changes can be implemented across multiple assets without introducing inconsistencies or requiring full redesigns.

Coordinated Material System

All assets were designed to work together, supporting different stages of the patient journey and clinical workflow.

Role-Based Design Strategy

Each piece was structured for a specific audience, from patient education to staff-driven screening.

Workflow-Aligned Execution

Design decisions reflect real-world use in clinical settings, from intake to patient follow-up.

Blueleaf Creative Delivered

A coordinated system of clinical trial materials designed to support both patient-facing communication and internal clinical workflows.

Patient-Facing Materials

  • Recruitment flyer design for quick patient awareness
  • Trifold brochure design for detailed patient education and take-home use

Clinical Staff Tools

  • Patient screening guide design for eligibility evaluation and intake workflows

System Development

  • Unified layout and hierarchy across all materials
  • Paragraph and character style systems for consistency
  • File organization supporting ongoing updates and reuse

Services Provided

This project combined brochure design, flyer design, and marketing materials design to create a coordinated clinical communication system that supports both patient engagement and internal workflow efficiency.

Brochure Design

Flyer Design

Marketing Materials Design

Results

The Airflow4 Clinical Trial Materials System improved how information is communicated across both patient and clinical staff interactions. Each piece now supports a specific role, allowing patients to move from awareness to understanding while enabling staff to efficiently evaluate eligibility.

The consistency across materials reduces confusion and creates a more cohesive experience throughout the patient journey. Patients encounter a clear progression of information, while staff benefit from tools that align with real-world workflows.

The system also improves long-term usability. With a structured file system and consistent design framework in place, updates can be made more efficiently as study requirements evolve, reducing the need for repeated design work and maintaining consistency across all materials.

COORDINATED MATERIAL SYSTEM

aligning patient-facing and staff-facing tools into one cohesive framework

IMPROVED PATIENT JOURNEY

from initial awareness through education and enrollment support

MORE EFFICIENT CLINICAL WORKFLOW

with tools designed for real-world intake and screening processes

Airflow4 Results Summary

Result Area Outcome Impact
System Coordination All materials aligned into a single, structured communication system. Reduced fragmentation and improved consistency across clinical sites.
Patient Communication Clear progression from flyer to brochure supports understanding and engagement. Improved patient ability to absorb and act on study information.
Clinical Workflow Screening guide supports fast, structured eligibility evaluation. Increased efficiency during intake and reduced screening friction.
Operational Efficiency Style-based file system supports consistent updates across all materials. Reduced need for repeated design work and improved long-term usability.

Meet the Designer Behind This Project

Leah Dossey designs catalogs and brochures with one goal in mind. Help you win more business. With 22+ years in print and digital design, I design catalogs that are easy to understand, on brand, and press-ready. You get clear communication, smart layout decisions, and files that move through production without surprises.

If your company needs help organizing technical information into clear, professional marketing materials, Blueleaf Creative can help.

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Serving clients nationwide and locally in Houston, Spring, The Woodlands, and Conroe.

Graphic designer, Leah Dossey holding a blue business card at Blueleaf Creative firm

Related Projects

Each component of this system can be explored in detail, including the recruitment flyer, trifold brochure, and patient screening guide.

Airflow4 Clinical Trial Recruitment Brochure

Trifold brochure designed to support patient education and enrollment with structured content and QR integration.

Clinical trial brochure panel with QR code linking to enrollment website

Airflow4 Patient Screening Guide

Patient screening guide to qualify patients for clinical trial study and quick reference for healthcare professionals.

Clinical trial patient screening guide design showing icon-based overview and structured eligibility layout

Airflow4 Clinical Trial Recruitment Flyer

Recruitment flyer designed for quick patient awareness and scalable use across clinical environments.

Clinical trial patient recruitment flyer design for Airflow4 study showing structured layout and patient information